R25G (p.Arg25Gly) variant of MYC (Myc proto-oncogene protein)
R25G (p.Arg25Gly) in MYC (Myc proto-oncogene protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
R25G (p.Arg25Gly) variant details
- p.Arg25Gly
- cosmic curated COSV99422
- Ensembl rs2130092281
- Missense
- Variant Prioritization Score for Impact Estimate 0.453
- CADD 28.80
- PolyPhen-2 0.01
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available