P12R (p.Pro12Arg) variant of MYC (Myc proto-oncogene protein)
P12R (p.Pro12Arg) in MYC (Myc proto-oncogene protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
P12R (p.Pro12Arg) variant details
- p.Pro12Arg
- ESP rs139294902
- ExAC rs139294902
- TOPMed rs139294902
- gnomAD rs139294902
- Missense
- Variant Prioritization Score for Impact Estimate 0.672
- CADD 21.70
- PolyPhen-2 0.03
- SIFT 0.06
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available