N26T (p.Asn26Thr) variant of MYC (Myc proto-oncogene protein)
N26T (p.Asn26Thr) in MYC (Myc proto-oncogene protein) is a missense change. Clinical records from EBI and UniProt describe it as benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
N26T (p.Asn26Thr) variant details
- p.Asn26Thr
- 1000Genomes rs4645959
- ESP rs4645959
- ExAC rs4645959
- TOPMed rs4645959
- Benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.594
- CADD 28.10
- PolyPhen-2 0.01
- SIFT 0.03
- EBI: Benign (in dbSNP:rs4645959)
- UniProt: Benign (in dbSNP:rs4645959)
- Most common in the African/African-American population (allele frequency 0.00036)
- Structural context available