L18Y (p.Leu18Tyr) variant of MYC (Myc proto-oncogene protein)
L18Y (p.Leu18Tyr) in MYC (Myc proto-oncogene protein) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
L18Y (p.Leu18Tyr) variant details
- p.Leu18Tyr
- gnomAD 8-127735516-TCC-T
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.305
- CADD 8.71
- Population evidence available
- Structural context available
- Literature evidence available