L18F (p.Leu18Phe) variant of MYC (Myc proto-oncogene protein)
L18F (p.Leu18Phe) in MYC (Myc proto-oncogene protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
L18F (p.Leu18Phe) variant details
- p.Leu18Phe
- cosmic curated COSV10438
- Ensembl rs1813639928
- Missense
- Variant Prioritization Score for Impact Estimate 0.561
- CADD 23.70
- PolyPhen-2 0.98
- SIFT 0.28
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available