F3L (p.Phe3Leu) variant of MYC (Myc proto-oncogene protein)
F3L (p.Phe3Leu) in MYC (Myc proto-oncogene protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
F3L (p.Phe3Leu) variant details
- p.Phe3Leu
- ExAC rs772459508
- gnomAD rs772459508
- Missense
- Variant Prioritization Score for Impact Estimate 0.482
- CADD 18.20
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 0.0003)
- Structural context available