E8S (p.Glu8Ser) variant of MYC (Myc proto-oncogene protein)
E8S (p.Glu8Ser) in MYC (Myc proto-oncogene protein) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
E8S (p.Glu8Ser) variant details
- p.Glu8Ser
- gnomAD 8-127736070-AC-A
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.286
- CADD 15.00
- Most common in the Non-Finnish European population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available