E8G (p.Glu8Gly) variant of MYC (Myc proto-oncogene protein)
E8G (p.Glu8Gly) in MYC (Myc proto-oncogene protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
E8G (p.Glu8Gly) variant details
- p.Glu8Gly
- cosmic curated COSV52376
- ExAC rs759986640
- gnomAD rs759986640
- Missense
- Variant Prioritization Score for Impact Estimate 0.378
- CADD 22.00
- PolyPhen-2 0.00
- SIFT 0.51
- Most common in the South Asian population (allele frequency 0.00023)
- Structural context available