E8* (p.Glu8Ter) variant of MYC (Myc proto-oncogene protein)
E8* (p.Glu8Ter) in MYC (Myc proto-oncogene protein) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
E8* (p.Glu8Ter) variant details
- p.Glu8Ter
- rs1490830929
- gnomAD 8-127736076-G-T
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.404
- CADD 9.37
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available
- Literature evidence available