D2Y (p.Asp2Tyr) variant of MYC (Myc proto-oncogene protein)
D2Y (p.Asp2Tyr) in MYC (Myc proto-oncogene protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
D2Y (p.Asp2Tyr) variant details
- p.Asp2Tyr
- cosmic curated COSV10500
- ExAC rs778595707
- TOPMed rs778595707
- gnomAD rs778595707
- Missense
- Variant Prioritization Score for Impact Estimate 0.547
- CADD 31.00
- PolyPhen-2 0.65
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available