A14T (p.Ala14Thr) variant of MYC (Myc proto-oncogene protein)
A14T (p.Ala14Thr) in MYC (Myc proto-oncogene protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
A14T (p.Ala14Thr) variant details
- p.Ala14Thr
- cosmic curated COSV10501
- ExAC rs770253839
- TOPMed rs770253839
- gnomAD rs770253839
- Missense
- Variant Prioritization Score for Impact Estimate 0.373
- CADD 14.90
- PolyPhen-2 0.00
- SIFT 0.51
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available