A14P (p.Ala14Pro) variant of MYC (Myc proto-oncogene protein)
A14P (p.Ala14Pro) in MYC (Myc proto-oncogene protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
A14P (p.Ala14Pro) variant details
- p.Ala14Pro
- ExAC rs770253839
- TOPMed rs770253839
- gnomAD rs770253839
- Missense
- Variant Prioritization Score for Impact Estimate 0.399
- CADD 18.30
- PolyPhen-2 0.24
- SIFT 0.12
- Most common in the East Asian population (allele frequency 2.6e-05)
- Structural context available