H26Q (p.His26Gln) variant of MUTYH (Adenine DNA glycosylase)
H26Q (p.His26Gln) in MUTYH (Adenine DNA glycosylase) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of Hereditary cancer-predisposing syndrome. The record also includes published literature and structural context.
H26Q (p.His26Gln) variant details
- p.His26Gln
- rs776396492
- ClinGen CA340137175
- ClinVar RCV002416631
- Uncertain significance
- Hereditary cancer-predisposing syndrome
- Missense
- ClinVar: Uncertain significance (Hereditary cancer-predisposing syndrome)
- EBI: Benign
- UniProt: Benign
- Structural context available
- Cited in: A practice guideline from the American College of Medical Genetics and Genomics and the National Society of Genetic… (PMID 25394175)