T10I (p.Thr10Ile) variant of MTOR (P42345)
T10I (p.Thr10Ile) in MTOR (P42345) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
T10I (p.Thr10Ile) variant details
- p.Thr10Ile
- Ensembl rs2100986588
- Missense
- Variant Prioritization Score for Impact Estimate 0.307
- REVEL 0.04
- CADD 23.20
- PolyPhen-2 0.01
- SIFT 0.02
- MutPred 0.73
- Most common in the Middle Eastern population (allele frequency 0.00018)
- Structural context available