T121A (p.Thr121Ala) variant of MSI1 (O43347)
T121A (p.Thr121Ala) in MSI1 (O43347) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data and structural context.
T121A (p.Thr121Ala) variant details
- p.Thr121Ala
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.717
- REVEL 0.79
- CADD 25.30
- PolyPhen-2 0.49
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available