L85F (p.Leu85Phe) variant of MSI1 (O43347)
L85F (p.Leu85Phe) in MSI1 (O43347) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
L85F (p.Leu85Phe) variant details
- p.Leu85Phe
- ExAC rs755234912
- gnomAD rs755234912
- Missense
- Variant Prioritization Score for Impact Estimate 0.649
- REVEL 0.65
- CADD 24.90
- PolyPhen-2 0.35
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available