G25W (p.Gly25Trp) variant of MSI1 (O43347)
G25W (p.Gly25Trp) in MSI1 (O43347) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
G25W (p.Gly25Trp) variant details
- p.Gly25Trp
- TOPMed rs1489462649
- gnomAD rs1489462649
- Missense
- Variant Prioritization Score for Impact Estimate 0.682
- REVEL 0.63
- CADD 28.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available