Y8Y (p.Tyr8Tyr) variant of MSH6 (DNA mismatch repair protein Msh6)
Y8Y (p.Tyr8Tyr) in MSH6 (DNA mismatch repair protein Msh6) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
Y8Y (p.Tyr8Tyr) variant details
- p.Tyr8Tyr
- rs746306598
- gnomAD 2-47783257-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.141
- CADD 8.49
- Most common in the South Asian population (allele frequency 0.00044)
- Structural context available
- Literature evidence available