V80I (p.Val80Ile) variant of MSH6 (DNA mismatch repair protein Msh6)

V80I (p.Val80Ile) in MSH6 (DNA mismatch repair protein Msh6) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of Hereditary nonpolyposis colorectal neoplasms; Hereditary cancer-predisposing syn. The record also includes structural context.

V80I (p.Val80Ile) variant details