S14T (p.Ser14Thr) variant of MSH6 (DNA mismatch repair protein Msh6)
S14T (p.Ser14Thr) in MSH6 (DNA mismatch repair protein Msh6) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of Hereditary cancer-predisposing syndrome; not provided. The record also includes published literature and structural context.
S14T (p.Ser14Thr) variant details
- p.Ser14Thr
- rs876660417
- ClinGen CA346734532
- ClinVar RCV002323336
- ClinVar RCV003126243
- Uncertain significance
- Hereditary cancer-predisposing syndrome; not provided
- Missense
- ClinVar: Uncertain significance (Hereditary cancer-predisposing syndrome; not provided)
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Structural context available
- Cited in: A practice guideline from the American College of Medical Genetics and Genomics and the National Society of Genetic… (PMID 25394175)