P12P (p.Pro12Pro) variant of MSH6 (DNA mismatch repair protein Msh6)
P12P (p.Pro12Pro) in MSH6 (DNA mismatch repair protein Msh6) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
P12P (p.Pro12Pro) variant details
- p.Pro12Pro
- rs760533525
- gnomAD 2-47783269-C-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.258
- CADD 13.80
- Most common in the Non-Finnish European population (allele frequency 5.8e-05)
- Structural context available
- Literature evidence available