L7L (p.Leu7Leu) variant of MSH6 (DNA mismatch repair protein Msh6)
L7L (p.Leu7Leu) in MSH6 (DNA mismatch repair protein Msh6) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
L7L (p.Leu7Leu) variant details
- p.Leu7Leu
- rs757815307
- gnomAD 2-47783254-G-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.204
- CADD 11.60
- Most common in the Non-Finnish European population (allele frequency 5e-05)
- Structural context available
- Literature evidence available