R3S (p.Arg3Ser) variant of MSH3 (DNA mismatch repair protein Msh3)
R3S (p.Arg3Ser) in MSH3 (DNA mismatch repair protein Msh3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
R3S (p.Arg3Ser) variant details
- p.Arg3Ser
- gnomAD 5-80654734-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.417
- REVEL 0.40
- CADD 23.60
- PolyPhen-2 0.59
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available