K35E (p.Lys35Glu) variant of MSH3 (DNA mismatch repair protein Msh3)
K35E (p.Lys35Glu) in MSH3 (DNA mismatch repair protein Msh3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
K35E (p.Lys35Glu) variant details
- p.Lys35Glu
- gnomAD 5-80654830-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.427
- REVEL 0.37
- CADD 24.30
- PolyPhen-2 0.10
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available