G32A (p.Gly32Ala) variant of MSH3 (DNA mismatch repair protein Msh3)
G32A (p.Gly32Ala) in MSH3 (DNA mismatch repair protein Msh3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
G32A (p.Gly32Ala) variant details
- p.Gly32Ala
- ExAC rs774577965
- gnomAD rs774577965
- Missense
- Variant Prioritization Score for Impact Estimate 0.479
- REVEL 0.36
- CADD 23.10
- PolyPhen-2 0.57
- SIFT 0.07
- Most common in the East Asian population (allele frequency 2.6e-05)
- Structural context available