L11F (p.Leu11Phe) variant of MSH2 (DNA mismatch repair protein Msh2)
L11F (p.Leu11Phe) in MSH2 (DNA mismatch repair protein Msh2) is a missense change. Clinical records from EBI and UniProt describe it as likely benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes structural context.
L11F (p.Leu11Phe) variant details
- p.Leu11Phe
- Ensembl rs2103868565
- Likely benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.626
- ESM-1b 1.00
- AlphaMissense 0.18
- EBI: Likely benign
- UniProt: Likely benign
- Structural context available