F19I (p.Phe19Ile) variant of MSH2 (DNA mismatch repair protein Msh2)
F19I (p.Phe19Ile) in MSH2 (DNA mismatch repair protein Msh2) is a missense change. Clinical records from EBI and UniProt describe it as benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.97 / 1. The record also includes population frequency data and structural context.
F19I (p.Phe19Ile) variant details
- p.Phe19Ile
- 1000Genomes rs141711342
- ESP rs141711342
- ExAC rs141711342
- TOPMed rs141711342
- Benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.967
- ESM-1b 1.00
- AlphaMissense 0.93
- EBI: Benign
- UniProt: Benign
- Population evidence available
- Structural context available