A15S (p.Ala15Ser) variant of MSH2 (DNA mismatch repair protein Msh2)
A15S (p.Ala15Ser) in MSH2 (DNA mismatch repair protein Msh2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
A15S (p.Ala15Ser) variant details
- p.Ala15Ser
- gnomAD 2-47403234-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.394
- REVEL 0.35
- ESM-1b 0.00
- AlphaMissense 0.09
- CADD 22.40
- PolyPhen-2 0.00
- SIFT 0.55
- Population evidence available
- Structural context available
- Literature evidence available