A15A (p.Ala15Ala) variant of MSH2 (DNA mismatch repair protein Msh2)
A15A (p.Ala15Ala) in MSH2 (DNA mismatch repair protein Msh2) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
A15A (p.Ala15Ala) variant details
- p.Ala15Ala
- rs876659170
- gnomAD 2-47403236-C-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.275
- CADD 14.20
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available