T71I (p.Thr71Ile) variant of MRE11 (P49959)
T71I (p.Thr71Ile) in MRE11 (P49959) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
T71I (p.Thr71Ile) variant details
- p.Thr71Ile
- gnomAD rs1947134384
- Missense
- Variant Prioritization Score for Impact Estimate 0.693
- REVEL 0.65
- CADD 24.00
- PolyPhen-2 0.70
- SIFT 0.17
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available