T71A (p.Thr71Ala) variant of MRE11 (P49959)
T71A (p.Thr71Ala) in MRE11 (P49959) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
T71A (p.Thr71Ala) variant details
- p.Thr71Ala
- gnomAD rs1947134490
- Missense
- Variant Prioritization Score for Impact Estimate 0.382
- REVEL 0.31
- CADD 21.20
- PolyPhen-2 0.06
- SIFT 0.31
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available