G58S (p.Gly58Ser) variant of MRE11 (P49959)

G58S (p.Gly58Ser) in MRE11 (P49959) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of Ataxia-telangiectasia-like disorder; Hereditary cancer-predisposing syndrome. The record also includes published literature and structural context.

G58S (p.Gly58Ser) variant details