F37I (p.Phe37Ile) variant of MRE11 (P49959)
F37I (p.Phe37Ile) in MRE11 (P49959) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
F37I (p.Phe37Ile) variant details
- p.Phe37Ile
- Ensembl rs781084066
- Missense
- Variant Prioritization Score for Impact Estimate 0.612
- REVEL 0.64
- CADD 22.60
- PolyPhen-2 0.04
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available