V9V (p.Val9Val) variant of MPL (Thrombopoietin receptor)
V9V (p.Val9Val) in MPL (Thrombopoietin receptor) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
V9V (p.Val9Val) variant details
- p.Val9Val
- rs1343948119
- gnomAD 1-43337875-C-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.223
- CADD 9.31
- Population evidence available
- Structural context available
- TpoR activation by high dosage of lusutrombopag: score 1.03
- Literature evidence available