V9L (p.Val9Leu) variant of MPL (Thrombopoietin receptor)
V9L (p.Val9Leu) in MPL (Thrombopoietin receptor) is a missense change. The record also includes variant effect predictions, experimental measurements, and structural context.
V9L (p.Val9Leu) variant details
- p.Val9Leu
- Ensembl rs2153916099
- Missense
- MetaLR 0.39
- MetaSVM -0.69
- SIFT 0.35
- Structural context available
- TpoR activation by high dosage of lusutrombopag: score 1.03