V23D (p.Val23Asp) variant of MPL (Thrombopoietin receptor)
V23D (p.Val23Asp) in MPL (Thrombopoietin receptor) is a missense change. The record also includes variant effect predictions, experimental measurements, and structural context.
V23D (p.Val23Asp) variant details
- p.Val23Asp
- Ensembl rs2153916124
- Missense
- MetaLR 0.29
- MetaSVM -0.56
- SIFT 0.00
- Structural context available
- TpoR activation by low dosage of Tpo: score 1.18