S25N (p.Ser25Asn) variant of MPL (Thrombopoietin receptor)
S25N (p.Ser25Asn) in MPL (Thrombopoietin receptor) is a missense change. The record also includes variant effect predictions, experimental measurements, and structural context.
S25N (p.Ser25Asn) variant details
- p.Ser25Asn
- Ensembl rs2153916128
- Missense
- MetaLR 0.70
- MetaSVM 0.01
- SIFT 0.07
- Structural context available
- TpoR activation by low dosage of Tpo: score 0.793