S24N (p.Ser24Asn) variant of MPL (Thrombopoietin receptor)
S24N (p.Ser24Asn) in MPL (Thrombopoietin receptor) is a missense change. The record also includes variant effect predictions, experimental measurements, and structural context.
S24N (p.Ser24Asn) variant details
- p.Ser24Asn
- Ensembl rs2153916127
- Missense
- MetaLR 0.14
- MetaSVM -0.93
- SIFT 0.01
- Structural context available
- TpoR activation by low dosage of Tpo: score 1.07