P17P (p.Pro17Pro) variant of MPL (Thrombopoietin receptor)
P17P (p.Pro17Pro) in MPL (Thrombopoietin receptor) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
P17P (p.Pro17Pro) variant details
- p.Pro17Pro
- rs2153916114
- gnomAD 1-43337899-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.264
- CADD 10.00
- Population evidence available
- Structural context available
- TpoR activation by low dosage of romi-peptide: score 1.12
- Literature evidence available