P17L (p.Pro17Leu) variant of MPL (Thrombopoietin receptor)
P17L (p.Pro17Leu) in MPL (Thrombopoietin receptor) is a missense change. The record also includes experimental measurements and structural context.
P17L (p.Pro17Leu) variant details
- p.Pro17Leu
- cosmic curated COSV10468
- gnomAD rs1190077369
- Missense
- Structural context available
- TpoR activation by low dosage of romi-peptide: score 1.12