L48F (p.Leu48Phe) variant of MPL (Thrombopoietin receptor)
L48F (p.Leu48Phe) in MPL (Thrombopoietin receptor) is a missense change. The record also includes experimental measurements and structural context.
L48F (p.Leu48Phe) variant details
- p.Leu48Phe
- Ensembl rs2153916243
- Missense
- Structural context available
- TpoR activation by high dosage of lusutrombopag: score 0.449