L254P (p.Leu254Pro) variant of MPL (Thrombopoietin receptor)

L254P (p.Leu254Pro) in MPL (Thrombopoietin receptor) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as likely pathogenic in the context of Congenital amegakaryocytic thrombocytopenia. The record also includes structural context.

L254P (p.Leu254Pro) variant details