L13I (p.Leu13Ile) variant of MPL (Thrombopoietin receptor)
L13I (p.Leu13Ile) in MPL (Thrombopoietin receptor) is a missense change. The record also includes variant effect predictions, experimental measurements, and structural context.
L13I (p.Leu13Ile) variant details
- p.Leu13Ile
- Ensembl rs2153916107
- Missense
- MetaLR 0.64
- MetaSVM -0.17
- SIFT 0.04
- Structural context available
- TpoR activation by low dosage of romi-peptide: score 1.69