G61V (p.Gly61Val) variant of MPL (Thrombopoietin receptor)
G61V (p.Gly61Val) in MPL (Thrombopoietin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
G61V (p.Gly61Val) variant details
- p.Gly61Val
- gnomAD 1-43338201-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.432
- REVEL 0.46
- MetaLR 0.54
- MetaSVM -0.42
- CADD 22.50
- PolyPhen-2 0.78
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available