G61E (p.Gly61Glu) variant of MPL (Thrombopoietin receptor)
G61E (p.Gly61Glu) in MPL (Thrombopoietin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
G61E (p.Gly61Glu) variant details
- p.Gly61Glu
- gnomAD 1-43338201-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.243
- REVEL 0.17
- MetaLR 0.28
- MetaSVM -0.89
- CADD 14.60
- PolyPhen-2 0.04
- SIFT 0.11
- Population evidence available
- Structural context available
- Literature evidence available