E84K (p.Glu84Lys) variant of MMUT (P22033)
E84K (p.Glu84Lys) in MMUT (P22033) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
E84K (p.Glu84Lys) variant details
- p.Glu84Lys
- NCI-TCGA Cosmic COSV1043
- NCI-TCGA Cosmic COSV9922
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.715
- REVEL 0.69
- CADD 22.70
- PolyPhen-2 0.28
- SIFT 0.31
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available