P37L (p.Pro37Leu) variant of MMAB (Q96EY8)
P37L (p.Pro37Leu) in MMAB (Q96EY8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
P37L (p.Pro37Leu) variant details
- p.Pro37Leu
- ExAC rs756081192
- gnomAD rs756081192
- Missense
- Variant Prioritization Score for Impact Estimate 0.279
- REVEL 0.22
- ESM-1b 0.00
- AlphaMissense 0.08
- CADD 23.50
- PolyPhen-2 0.35
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available