F145L (p.Phe145Leu) variant of MMAB (Q96EY8)
F145L (p.Phe145Leu) in MMAB (Q96EY8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
F145L (p.Phe145Leu) variant details
- p.Phe145Leu
- gnomAD rs1452974630
- Missense
- Variant Prioritization Score for Impact Estimate 0.367
- REVEL 0.42
- ESM-1b 1.00
- AlphaMissense 0.90
- CADD 7.08
- PolyPhen-2 0.17
- SIFT 0.09
- Most common in the East Asian population (allele frequency 0.00011)
- Structural context available