S63R (p.Ser63Arg) variant of MLH3 (DNA mismatch repair protein Mlh3)
S63R (p.Ser63Arg) in MLH3 (DNA mismatch repair protein Mlh3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
S63R (p.Ser63Arg) variant details
- p.Ser63Arg
- gnomAD rs1443431758
- Missense
- Variant Prioritization Score for Impact Estimate 0.0681
- REVEL 0.05
- CADD 2.17
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available