S33R (p.Ser33Arg) variant of MLH3 (DNA mismatch repair protein Mlh3)
S33R (p.Ser33Arg) in MLH3 (DNA mismatch repair protein Mlh3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
S33R (p.Ser33Arg) variant details
- p.Ser33Arg
- gnomAD rs1197141918
- Missense
- Variant Prioritization Score for Impact Estimate 0.653
- REVEL 0.88
- CADD 24.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available